Most horse trainers rest during their down time, or perhaps play a bit of golf.

Rick Worthington spends his at Royal North Shore hospital.

As he undergoes a new drug trial for melanoma, Worthington says nothing will get in the way of doing what he loves most - training horses.

"I guess it's a bit like some of our great pioneers. In times like that, you've got to have a bit of guts and grit," Worthington said.

"I'm still there watching all my horses doing gallops. I'm not bedridden or sitting at home whingeing and whining or playing the victim.

"I've been in the industry since the 80s and it's my passion. I want to do what I love."

Worthington will bring Milbo to Saturday's Gimcrack Stakes at Randwick and expects his filly to impress despite a wide barrier.

"The best part is that she's not just a one-dimensional type of horse. She's a horse that can sit off the speed and then have a nice finish," he said.

"She's shown she's an athlete."

Meanwhile, Cheryl Roberts will unleash her first ever Randwick runner in the form of filly Divajeu.

A former legal consultant, Roberts and her vet husband Tim play a large role in the pre-training of horses from the Chris Waller stable at their Boynton Park facility.

"Tim and I lived in South Africa for 20 years working at a clinic, and coming back to Australia I've been lucky enough to do many things," Roberts said.

"I thought this was the next step for me, to use the skills I've gained over my career."

Divajeu impressed with a win in her barrier trial last month and Roberts said Gimcrack punters would see her filly's enthusiastic style once again.

"She did everything I asked her to do. She jumped well and ran nicely, and has pulled up well. She was never under pressure," she said.

"She's going as well as any young horse could."