Animal Kingdom galloped to a resounding victory in the $US10 million ($A9.62 million) Dubai World Cup here on Saturday in the process becoming the ninth American-trained winner in the 18-year history of the world's richest race.

Trained by England-born Graham Motion, the five-year-old tracked front-running Royal Delta before jockey Joel Rosario sent him clear early in the home straight.

He won by two lengths from fast-closing English raider Red Cadeaux, with another English runner Planteur replicating his finishing position 12 months ago in third, a further 4 3/4 lengths in arrears.

Victory for Animal Kingdom was just reward for connections of a horse that was due to contest last year's World Cup until he got injured in the build-up.

Australia's Arrowfield Stud recently acquired a significant share in the horse from the American owners, Team Valor - the Australian national anthem ringing out in honour of the win at the presentation ceremony - and is expected to stand him as a stallion in due course.

Before then, Animal Kingdom has his sights on the Royal Ascot meeting in June.

One of the American owners, Barry Irwin said he had expected another great race from his injury-prone star.

"It has been up down and up and down with this horse," he said.

"I always thought he had another great race in him and it almost came in the Breeders' Cup Mile last year but it has certainly come true here."

Stall 12 had been billed as an impediment to Animal Kingdom, who habitually likes to settle in rear before charging home with a late run.

However, after a moderate break this time, Rosario took the horse forward so that he emerged from the first bend on Royal Delta's tail.

Godolphin's Hunter's Light, the much-fancied local hope, stalked the pace but raced with too much zest to sustain his effort.

As the winner powered clear Red Cadeaux came out of the pack to claim $US2 million ($A1.92 million) for finishing second.

Animal Kingdom redressed the balance for American horses, which have suffered several disappointments since the World Cup surface was changed from dirt to a synthetic surface three years ago.

The horse was already proven on synthetics, having won the Spiral Stakes at Turfway Park, in Kentucky, ahead of his victory in the 2011 Kentucky Derby.

The race was deprived of last year's winner at the eleventh hour when Monterosso was withdrawn in the morning through lameness.

Monterosso's intended jockey, Mickael Barzalona, switched to African Story but the combination made no show.