Hello Youmzain has continued the trend of three-year-olds winning Group One sprints this season with a clear-cut success in the Sprint Cup at Haydock.
Ten Sovereigns and Advertise - who both missed Saturday's event - have triumphed for their age group in top-level contests this season.
James Doyle had the Kevin Ryan-trained colt up in the lead with Invincible Army.
Two furlongs out the pair got a break on the field and once Hello Youmzain saw off his rival, he just needed to hold any challengers emerging from the pack.
Former winner The Tin Man and stablemate Brando made late bids, but the 9-2 co-favourite stuck it out well.
The Tin Man ran his best race of the season for second while German raider Waldpfad flew home for third.
Hello Youmzain had been off the track since finishing third in the Commonwealth Cup at Royal Ascot in June.
"We decided after Ascot that we'd be patient with him as it's not all about this year," Ryan said.
"These horses don't come around very often and although we gave him a tentative entry in the Nunthorpe, this race was always the plan.
"He's such a young horse and a big horse as well. You shouldn't wish your life away, but he's going to mature and he'll be a stronger horse next year. He's very exciting.
"He'll have one more run this year on Champions Day at Ascot and then we'll put him away for next season."