Big-race performer Streama will be chasing her second Group One win this year after bouncing back to her best form at Caulfield on Saturday.
The four-year-old took her career haul of race wins to seven - all at Group or Listed level - when she won the Group Two Tristarc Stakes (1400m).
The Australian Oaks winner will now be aimed at the Group One Myer Classic (1600m) at Flemington on November 3.
Trainer Guy Walter said the reigning New South Wales Horse of the Year was a versatile mare who should appreciate racing at the mile distance.
"That's our target and she can run on wet or dry and she can come from behind or she can lead," Walter said.
"She's a terrific mare and it's great to see her show the Melbourne people what she can do."
Walter said that from barrier 14 he and jockey Hugh Bowman had no plan to set the pace.
"We didn't really go out with the intention of leading but obviously from that gate you've got to have an open mind," he said.
"Hughie rode her superbly - she's a great little mare and I hope she can go on to the mile."
Streama beat Pear Tart by 1-1/4 lengths while Mosheen, the $3.10 favourite, struggled to the line in sixth place.