Fake Love has been scratched from the Magic Millions and Readily Availabull is battling to shake off a hoof injury threatening to derail his campaign.
Fake Love was scratched on Friday after failing to recover sufficiently from lameness in her near foreleg.
"While this is frustrating for all concerned, the well-being of the horse is our priority and we look forward to getting her sound, with lofty targets ahead for the second half of the season," the Ciaron Maher-David Eustace stable said in a statement.
John Sargent is hoping Readily Availabull can recover before the scratching deadline on Saturday morning to enable him to run in the Millions.
"His hoof has been poulticed and they can come right very quickly," Sargent said.
"Things are certainly up in the air and it depends how quickly he reacts to the poultice.
"He wouldn't run if he wasn't 100 per cent. He's too good a horse."
In contrast to the drama surrounding Fake Love and Readily Availabull, trainer Desleigh Forster is delighted with Apache Chase ahead of the Magic Millions Guineas (1400m).
"His work on Tuesday was fantastic and he looks super," Forster said."He's got the one gate and it's really up to Taylor (Marshall) and him now. We can't do any more than what we've done."
Apache Chase has an unblemished record in races at 1400 metres and beyond winning three times including his latest appearance when he claimed the Group Three Vo Rogue Plate (1400m) at Eagle Farm on Boxing Day.
"We were very confident going into the Vo Rogue especially getting out the 1400 metres on the big track at Eagle Farm," Forster said.
"The further he goes the better this horse will be."
Forster is confident racing at the Gold Coast for the first time will not prove a problem for Apache Chase.
"He's pretty adaptable and not much seems to worry him," she said.
"He jumps and puts himself in the race and cruises along at a good tempo."
Apache Chase is at $14 with TAB fixed odds for the Guineas with the Tony Gollan-trained Isotope a $2.50 favourite.