Trips to Paris and California are on the agenda for The Fugue after she bounced back to her brilliant best in the Yorkshire Oaks.
With Scintillula having set a fierce pace, William Buick appeared keen to play his cards late on the market-leader, but she ranged up menacingly in the straight.
Smart three-year-old Venus De Milo did her best to fend off her older rival, but was simply not in the same league as The Fugue breezed clear for an emphatic four-length verdict.
The Prix de l'Arc de Triomphe is now firmly in trainer John Gosden's sights, as is a trip to the Breeders' Cup.
The Fugue finished a luckless third at Santa Anita in last November's Filly & Mare Turf over the turning mile and a quarter (2000m), and this year could take on the boys over a mile and half in the Breeders' Cup Turf.
"The Vermeille (Longchamp, September 15) would come into consideration for her next run and after that there is the Arc and I do think she is that level," Gosden said.
"If the ground is good or faster, or even good to soft, that would be a strong possibility, but she hates bottomless ground.
"She went to the Breeders' Cup last year and didn't have much luck, but we'd be keen to go back.
"There is the Filly & Mare, but the mile-and-a-half race (Breeders' Cup Turf) could be more suitable for her."