Vancouver will bid to end a hoodoo that has stretched for almost a quarter of a century when he returns in the San Domenico Stakes at Rosehill.

The Gai Waterhouse-trained colt is favourite to become the first Golden Slipper winner since Tierce in 1991 to add the Group Three sprint to his record.

The San Domenico Stakes (1100m) is the feature race on Saturday's program and has attracted an eclectic mix of eight runners.

One-time Golden Slipper favourite Headwater will resume for Hawkes Racing along with Haptic from the powerful Godolphin stable.

Chris Waller is banking on race fitness giving Japonisme an edge when he steps up to stakes company for the first time following a hat-trick of winter wins.

The country-trained Alart is the only filly in the race and her presence has prompted bush jockey Greg Ryan to make a rare trip to town.

Ryan passed a career milestone at Scone on Sunday when he rode winner No.3323, putting him second on the all-time list of Australia's most successful jockeys by number of winners.

He primarily rides on the NSW bush circuit and Saturday's visit to town will be his first since he competed in the Country Championship Final during the Sydney autumn carnival.