With Omei Sword scratched from the Flight Stakes, the remaining fillies are lining up for the ultimate redemption in a Group One race.

In a field littered with hard-luck stories, Omei Sword contributed her own chapter after her spring ended on Thursday morning when she was found to be suffering a respiratory infection.

The Chris Waller-trained filly's withdrawal rocketed Yankee Rose to $1.90 favouritism for the Group One Flight (1600m) at Randwick on Saturday.

Yankee Rose was heavily backed to win the Golden Rose but after unexpectedly finding the lead, she found herself outside her comfort zone and finished sixth.

Trainer David Vandyke said he would tell jockey Blake Shinn to seek cover with Yankee Rose on Saturday.

Omei Sword had been as short as $1.60 for the Flight, but despite her absence Waller retains two strong hopes for the race.

Awoke shares the third line of betting with the James Cummings-trained Tea Rose Stakes runner-up Skylight Glow at $6, and Sezanne is a $9.50 chance.

Of the six runners engaged after scratchings, four come out of the traditional lead-up Group Two Tea Rose at Randwick on September 17.

Awoke couldn't find her way through traffic when seventh behind stablemate Foxplay in that race at Randwick on September 17, while Sezanne finished fourth.

"I contemplated running Awoke on Sunday in the Edward Mainfold (Stakes) at Flemington but it's a Group One in our own backyard," Waller said.

"I can't really say she's going any worse than the likes of Foxplay and Sezanne that were obviously the benchmark last start. She's a good chance of running in the top three."

Sezanne also encountered her share of bad luck in the Tea Rose.

"She got back and had to cover a bit of extra ground and was beaten a neck," Waller said.

"She's got some upside to her. She can really improve."

Global Glamour's co-trainer Adrian Bott said she cost herself the Tea Rose by over-racing and finishing sixth, less than a length behind the Waller-trained Foxplay.

"She can be a little bit quirky and uptight at times," Bott said.

"If she can put it all together and take a deep breath and learn to relax on Saturday she'll be right there in the finish."

"I think there's plenty in the tank for her to go on down to Melbourne but this is the main target."

Bott's senior training partner Gai Waterhouse is looking for back-to-back victories in a race she has won eight times in the past 20 years.

John Thompson-trained Bridle Lane will have to make major improvement to win the Flight after she finished second in a four-horse midweek race at her last start.