Derby hopes for the promising Prince Of Penzance were dashed last season but trainer Darren Weir has him back on track for what he hopes will be a successful summer campaign.

Prince Of Penzance showed he was a horse with upside when he won over 2000-metres at Flemington in May despite doing a lot wrong during the race.

The win put the Group One Queensland Derby on the radar but that option was out of play just as quickly after Prince Of Penzance was found to have a small chip in a fetlock which required surgery.

The gelding makes his return as a four-year-old in Saturday's Western Health Handicap (1410m) at Flemington and has been installed an $8.50 chance in an open market.

"He did a lot wrong in his last run but he's grown up in himself and he's a lot better," Weir said.

"He has matured in himself and in his brain as well, so we're hoping that will help him."

The Mornington Cup in February is the likely target for Prince Of Penzance with the winner earning a ballot exemption for next year's Caulfield Cup.

Michelle Payne has ridden Prince Of Penzance in all five starts which have netted three wins and she retains the ride on Saturday.

"He's had two trials and Michelle has ridden him. She has been happy with him," Weir said.

Stablemate Flying Hostess is entered for the same race but Weir said the mare would run at Moonee Valley on Friday night.

The former Mike Moroney-trained Zabisco makes his debut for Weir in the Dorevitch Pathology Handicap (1720m).

Weir said Zabisco had been doing beach work for a change of environment and the trainer expects to learn more about the horse on Saturday.

"He's been down the beach. We just thought we'd try something different and we've taken all the gear off him," Weir said.

"He's in good order."