The first three overseas-trained horses across the line in the Melbourne Cup have left Australia in search of further international riches.

Third placegetter Jakkalberry, luckless Mount Athos and Red Cadeaux will have their next start in the Japan Cup in Tokyo on November 25.

They departed the Werribee quarantine centre, home to a record number of internationals for the 2012 spring carnival, on Tuesday.

Mount Athos, who raced wide before his fifth placing to Green Moon in the Melbourne Cup, will be accompanied on his flight to Japan by trainer Luca Cumani's travelling foreman Charlie Henson.

"The Cup from our point of view was obviously disappointing because Mount Athos was flying at the end and just ran out of time," Henson said.

Red Cadeaux, beaten by the narrowest margin in Cup history in 2011, leaves Australia after finishing eighth this year.

The 2011 Melbourne Cup winner Dunaden will remain at Werribee until November 25.

The French stayer, who finished 14th as favourite last week, will have his next start in Hong Kong.

He will head to the Asian racing stronghold with the Cumani-trained My Quest For Peace where they will race in next month's Hong Kong Vase, a race Dunaden won last year.