Rebel Dane will be missing from the Memsie Stakes but eight other Group One winners are in the quality line-up for the feature race at Caulfield.
The Gary Portelli-trained Rebel Dane was due to contest the first Group One in Australia for the season on Saturday but a stone bruise ruled him out.
The weight-for-age feature has 16 quality nominations including the Peter Moody-trained pair Moment Of Change and Dissident and Boban and Foreteller from the Chris Waller stable.
Caulfield Cup winner Fawkner has been entered, as has Cox Plate runner-up Happy Trails, outstanding New Zealand mare Silent Achiever, and last year's Australian Cup winner Super Cool.
High profile galloper Puissance De Lune will be chasing his first Group One victory, while the Hawkes Racing team has nominated Group Two winners Messene and Toydini.
Puissance De Lune galloped over 800m between races with a companion at Warrnambool on Monday, pleasing trainer Darren Weir ahead of his second-up assignment.
"He just had a nice bit of sharp work today and I thought he worked quite well," Weir said.
Sertorius, runner-up to Moment Of Change in the Futurity Stakes over the course and distance first-up last campaign, is scheduled to make his return with his regular jockey Ryan Maloney hoping his appeal against suspension on Tuesday will result in at least a penalty reduction.
Super Cool finished third to superstar stablemate Atlantic Jewel first-up in the Memsie last year and is entered to make his return after being given the autumn off by trainer Mark Kavanagh.
The five-year-old gelding, who won the Group One Australian Cup as a three-year-old, has not raced since his ninth in last year's Melbourne Cup.
Kavanagh said the gelding was jaded after the 2013 spring carnival.
"It was our plan all along to give him the autumn off and get back and concentrate on this spring," Kavanagh said.
"I would be of the opinion that he's a much better horse going into this spring than he was last year."
The Cox Plate and Mackinnon Stakes are expected to be Super Cool's main spring targets.
Portelli will give Rebel Dane time to recover before deciding on another spring target for last year's Sir Rupert Clarke Stakes winner.